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Multiple Choice

Among the following, which adverse effect is listed for evinacumab?

Evinacumab, a monoclonal antibody against ANGPTL3 used for certain severe lipid disorders, is most commonly associated with upper respiratory tract infections. In its clinical trials and labeling, nasopharyngitis stands out as the adverse effect most frequently reported. This type of infection-related symptom—such as a stuffy or runny nose, sore throat, or mild fever—appears more commonly than other listed effects. Dizziness, rash, and fatigue can occur with many medications, including biologics, but they are less characteristic for evinacumab and are reported less consistently than nasopharyngitis.

Evinacumab, a monoclonal antibody against ANGPTL3 used for certain severe lipid disorders, is most commonly associated with upper respiratory tract infections. In its clinical trials and labeling, nasopharyngitis stands out as the adverse effect most frequently reported. This type of infection-related symptom—such as a stuffy or runny nose, sore throat, or mild fever—appears more commonly than other listed effects.

Dizziness, rash, and fatigue can occur with many medications, including biologics, but they are less characteristic for evinacumab and are reported less consistently than nasopharyngitis.