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Multiple Choice

Inclisiran's therapeutic goal includes reducing which lipid parameter?

Inclisiran lowers LDL-C by silencing PCSK9 production in the liver. With less PCSK9, more LDL receptors remain on hepatocytes to clear LDL particles from the blood, so LDL-cholesterol levels fall. This makes reducing LDL-C the therapeutic goal. It does not dramatically raise HDL-C, and it does not increase LDL-C or have no effect on cholesterol.

Inclisiran lowers LDL-C by silencing PCSK9 production in the liver. With less PCSK9, more LDL receptors remain on hepatocytes to clear LDL particles from the blood, so LDL-cholesterol levels fall. This makes reducing LDL-C the therapeutic goal. It does not dramatically raise HDL-C, and it does not increase LDL-C or have no effect on cholesterol.