Niacin lowers VLDL and LDL by inhibiting the release of which molecule from adipose tissue?

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Multiple Choice

Niacin lowers VLDL and LDL by inhibiting the release of which molecule from adipose tissue?

Niacin lowers VLDL and LDL by cutting adipose tissue lipolysis, which reduces the release of free fatty acids into the bloodstream. Less free fatty acid arrives at the liver means less substrate for hepatic triglyceride synthesis, so the liver secretes less VLDL. Since LDL largely comes from VLDL after triglyceride removal, LDL levels fall as well. The key molecule whose release is inhibited from adipose tissue is free fatty acids. Glucose, amino acids, and cholesterol are not the linchpin substrate driving VLDL production in this mechanism.

Niacin lowers VLDL and LDL by cutting adipose tissue lipolysis, which reduces the release of free fatty acids into the bloodstream. Less free fatty acid arrives at the liver means less substrate for hepatic triglyceride synthesis, so the liver secretes less VLDL. Since LDL largely comes from VLDL after triglyceride removal, LDL levels fall as well. The key molecule whose release is inhibited from adipose tissue is free fatty acids. Glucose, amino acids, and cholesterol are not the linchpin substrate driving VLDL production in this mechanism.

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