Omega-3 ethyl esters have which of the following effects on triglycerides and HDL-C?

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Multiple Choice

Omega-3 ethyl esters have which of the following effects on triglycerides and HDL-C?

Omega-3 ethyl esters work mainly by lowering how much triglyceride the liver puts into VLDL and by enhancing the clearance of triglyceride-rich particles. Because of that, triglyceride levels go down. They can also cause a small, clinicaly meaningful uptick in HDL-C in many patients, though the rise is modest and not guaranteed. So the statement that they lower triglycerides and may modestly raise HDL-C captures both the primary effect and the secondary, modest HDL-C change. The other options miss either the triglyceride-lowering effect, or suggest an opposite or absent effect on triglycerides, or focus only on HDL-C without noting the triglyceride reduction.

Omega-3 ethyl esters work mainly by lowering how much triglyceride the liver puts into VLDL and by enhancing the clearance of triglyceride-rich particles. Because of that, triglyceride levels go down. They can also cause a small, clinicaly meaningful uptick in HDL-C in many patients, though the rise is modest and not guaranteed.

So the statement that they lower triglycerides and may modestly raise HDL-C captures both the primary effect and the secondary, modest HDL-C change. The other options miss either the triglyceride-lowering effect, or suggest an opposite or absent effect on triglycerides, or focus only on HDL-C without noting the triglyceride reduction.

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