Enhance your knowledge of antihyperlipidemics and lipid management. Study with multiple choice questions and detailed explanations. Ace your test!

Multiple Choice

What is the generic name for the bile-acid sequestrant used in lipid management?

Cholestyramine is a bile acid sequestrant, a resin that binds bile acids in the intestine and prevents their reabsorption. By lowering the reabsorbed bile acids, the liver increases conversion of cholesterol to bile acids and upregulates LDL receptors, which pulls more LDL cholesterol from the blood and lowers LDL-C. Among the options, this is the classic generic name for a bile acid sequestrant. Other agents like colestipol and colesevelam are also bile acid sequestrants, but ezetimibe is not a bile acid sequestrant—it inhibits intestinal cholesterol absorption instead.

Cholestyramine is a bile acid sequestrant, a resin that binds bile acids in the intestine and prevents their reabsorption. By lowering the reabsorbed bile acids, the liver increases conversion of cholesterol to bile acids and upregulates LDL receptors, which pulls more LDL cholesterol from the blood and lowers LDL-C. Among the options, this is the classic generic name for a bile acid sequestrant. Other agents like colestipol and colesevelam are also bile acid sequestrants, but ezetimibe is not a bile acid sequestrant—it inhibits intestinal cholesterol absorption instead.