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Multiple Choice

Which adverse effect is associated with ezetimibe?

Ezetimibe inhibits intestinal cholesterol absorption, and its adverse effect profile is notable for possible hepatotoxicity—specifically elevations in liver enzymes, which can be more likely when used with a statin. This makes hepatotoxicity the adverse effect most associated with ezetimibe. The other options—hypotension, arrhythmia, and photosensitivity—are not typical effects of ezetimibe and are not the main safety concern with this drug. If liver enzymes rise, clinicians monitor and may adjust therapy, especially when statins are involved.

Ezetimibe inhibits intestinal cholesterol absorption, and its adverse effect profile is notable for possible hepatotoxicity—specifically elevations in liver enzymes, which can be more likely when used with a statin. This makes hepatotoxicity the adverse effect most associated with ezetimibe. The other options—hypotension, arrhythmia, and photosensitivity—are not typical effects of ezetimibe and are not the main safety concern with this drug. If liver enzymes rise, clinicians monitor and may adjust therapy, especially when statins are involved.