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Multiple Choice

Which adverse effect is listed for ezetimibe?

Main concept: the safety signal most associated with ezetimibe is potential liver toxicity, especially when used with a statin. Ezetimibe works by blocking intestinal cholesterol absorption, and while it’s generally well tolerated, safety data include occasional elevations in liver enzymes. This makes hepatotoxicity the adverse effect typically listed for ezetimibe, particularly in combination therapy, so clinicians monitor liver function tests and watch for signs of liver injury. GI symptoms or rash can occur with many drugs but are not the hallmark adverse effect for ezetimibe, and hair loss is not a recognized issue with this medication.

Main concept: the safety signal most associated with ezetimibe is potential liver toxicity, especially when used with a statin. Ezetimibe works by blocking intestinal cholesterol absorption, and while it’s generally well tolerated, safety data include occasional elevations in liver enzymes. This makes hepatotoxicity the adverse effect typically listed for ezetimibe, particularly in combination therapy, so clinicians monitor liver function tests and watch for signs of liver injury. GI symptoms or rash can occur with many drugs but are not the hallmark adverse effect for ezetimibe, and hair loss is not a recognized issue with this medication.