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Multiple Choice

Which of the following is a reported side effect of bempedoic acid?

The main concept here is recognizing a known adverse effect of bempedoic acid. Bempedoic acid lowers LDL-C by inhibiting ATP citrate lyase in the liver, but it also has a tendency to raise serum uric acid levels, which can precipitate gout in some patients. That association is well documented in clinical data and labeling, making hyperuricemia a reported side effect of this drug. The other options aren’t typical adverse effects linked to bempedoic acid—hepatotoxicity, hypokalemia, and photosensitivity aren’t commonly reported with this medication.

The main concept here is recognizing a known adverse effect of bempedoic acid. Bempedoic acid lowers LDL-C by inhibiting ATP citrate lyase in the liver, but it also has a tendency to raise serum uric acid levels, which can precipitate gout in some patients. That association is well documented in clinical data and labeling, making hyperuricemia a reported side effect of this drug.

The other options aren’t typical adverse effects linked to bempedoic acid—hepatotoxicity, hypokalemia, and photosensitivity aren’t commonly reported with this medication.