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Multiple Choice

Which of the following is a nonpharmacologic modification to reduce cholesterol?

Lowering dietary saturated fat and cholesterol is a lifestyle change that can lower cholesterol without medications. Saturated fats tend to raise LDL cholesterol by increasing hepatic cholesterol synthesis and reducing the clearance of LDL particles, so cutting them back lowers LDL and total cholesterol. The other options would not help and in fact can worsen lipid levels: increasing total fat or dietary cholesterol tends to raise cholesterol, and avoiding exercise removes a powerful nonpharmacologic way to improve the lipid profile.

Lowering dietary saturated fat and cholesterol is a lifestyle change that can lower cholesterol without medications. Saturated fats tend to raise LDL cholesterol by increasing hepatic cholesterol synthesis and reducing the clearance of LDL particles, so cutting them back lowers LDL and total cholesterol. The other options would not help and in fact can worsen lipid levels: increasing total fat or dietary cholesterol tends to raise cholesterol, and avoiding exercise removes a powerful nonpharmacologic way to improve the lipid profile.