Which statement about omega-3 ethyl esters is correct regarding HDL-C?

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Multiple Choice

Which statement about omega-3 ethyl esters is correct regarding HDL-C?

The key idea is how omega-3 ethyl esters affect different parts of the lipid profile. These agents mainly lower triglycerides by reducing hepatic VLDL production and increasing clearance of TG-rich lipoproteins. Because HDL-C is not the primary target of their action, the change in HDL-C tends to be small rather than large. In practice, you’ll see a modest uptick in HDL-C or, at worst, little to no change, while triglycerides drop more substantially. This makes the statement that HDL-C is modestly increased the most accurate reflection of their effect. The other possibilities imply a large or no effect on HDL-C, which isn’t supported by typical responses to omega-3 ethyl esters.

The key idea is how omega-3 ethyl esters affect different parts of the lipid profile. These agents mainly lower triglycerides by reducing hepatic VLDL production and increasing clearance of TG-rich lipoproteins. Because HDL-C is not the primary target of their action, the change in HDL-C tends to be small rather than large.

In practice, you’ll see a modest uptick in HDL-C or, at worst, little to no change, while triglycerides drop more substantially. This makes the statement that HDL-C is modestly increased the most accurate reflection of their effect.

The other possibilities imply a large or no effect on HDL-C, which isn’t supported by typical responses to omega-3 ethyl esters.

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