Which statement best describes the cause of hyperlipidemia in nephrotic syndrome?

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Hyperlipidemia in nephrotic syndrome mainly comes from the liver ramping up lipoprotein production in response to hypoalbuminemia from urinary protein loss. The liver increases synthesis of apolipoproteins and lipoproteins, especially VLDL, which elevates circulating cholesterol and triglycerides and can lead to higher LDL after metabolism. While reduced clearance of lipoproteins also plays a role, the driving force is the increased hepatic production. The other ideas—decreased hepatic lipoprotein synthesis, enhanced LDL clearance, or no effect on hepatic lipid production—do not explain the lipid rise seen in nephrotic syndrome.