Which statement is true regarding the HDL-C effect of omega-3 ethyl esters?

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Multiple Choice

Which statement is true regarding the HDL-C effect of omega-3 ethyl esters?

Omega-3 ethyl esters mainly lower triglycerides, but their effect on HDL-C tends to be small. In clinical studies, HDL-C often rises slightly or stays nearly the same, with changes that are modest rather than large. This makes a modest increase the best-supported statement. The primary action of these agents is reduced hepatic VLDL triglyceride production and faster clearance of TG-rich particles, while HDL-C changes are secondary and generally limited. A significant decrease or a dramatic increase in HDL-C isn’t seen consistently, and claiming no effect ignores the common small uptick observed in many patients.

Omega-3 ethyl esters mainly lower triglycerides, but their effect on HDL-C tends to be small. In clinical studies, HDL-C often rises slightly or stays nearly the same, with changes that are modest rather than large. This makes a modest increase the best-supported statement. The primary action of these agents is reduced hepatic VLDL triglyceride production and faster clearance of TG-rich particles, while HDL-C changes are secondary and generally limited. A significant decrease or a dramatic increase in HDL-C isn’t seen consistently, and claiming no effect ignores the common small uptick observed in many patients.

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